CFAR Network of Integrated Clinical Systems (C-NICS)

  • Principal Investigator(s): Ken Mayer, MD
  • Study Contact:, Ken Mayer, Tel: 617-927-6087, kmayer@fenwayhealth.org
  • Description of Subjects: 30,000 PLHIV in care at 8 HIV primary care centers
  • Location (Domestic vs. International): Fenway Health; UNC; UAB; Case Wester; UCSD; UCSF; U Wash
  • Enrollment Period: 2005-ongoing
  • Enrollment Goal: open cohort, >30,000 PLHIV.
  • Key Exclusion and Inclusion Criteria: HIV-infected and in care at one of the participating sites is required to be part of CNICS, but Fenway has had an EHR since 1997, so case-control studies with uninfected patients are also feasible
  • Available Biological Specimens and Data: Yes, Blood, serum, or plasma, Peripheral Blood Mononuclear Cells, Other (Cell Pellets)
  • How to Request Accessemail study contact directly at cgrasso@fenwayhealth.org
  • Link to Cohort Website: http://www.uab.edu/cnics/
  • Available Data Description: Demographics, risk factor, death data and longitudinal lab values (including CD4 and viral load), diagnosis, medication, encounters, and patient reported outcomes.
  • Other Information: The CFAR Network of Integrated Clinical Systems (CNICS) research network, is a NIH sponsored study, which is the first electronic medical records-based resource network poised to integrate clinical data from the large and diverse population of HIV-infected persons. CNICS supports HIV clinical outcomes and comparative effectiveness research using data collected from patients receiving care at one of 8 US-funded Center for AIDS Research (CFAR) sites. Fenway Health is one of the eight sites and has participated in this study since 2001. CNICS directly reflects the outcomes of clinical decisions and management options made daily in the care of HIV infected individuals and is helping to evaluate HIV treatment interventions under the real world conditions of a primary care practice.