Clinical Trials

BIDMC’s AIDS Malignancy Program is a core site for the AIDS Malignancy Consortium (AMC). This affiliation provides patients with access to a portfolio of clinical trials and other science-based studies available nationwide through the National Cancer Institute and the US National Institutes of Health. BIDMC also offers clinical trials as a member of the Dana-Farber/Harvard Cancer Center.

Adolescent Master Protocol for Participants 18 Years of Age and Older (AMP Up) – Currently Enrolling

This is a prospective cohort study designed to define the impact of HIV infection and antiretroviral therapy (ART) on young adults with perinatal HIV infection (YAPHIV) as they transition into adulthood. A group of uninfected young adults from a similar sociodemographic background and age distribution will be enrolled for comparison.

The Division at Brigham is actively involved in a variety of clinical research activities related to novel therapeutics. In particular, they have on-going studies related to the treatment of resistant bacterial pathogens, fungai, and HIV. They are active participants in the AIDS Clinical Trials Group (ACTG) and the HIV Vaccine Trials Network (HVTN). If you are interested in learning more about their Clinical Research Program, please contact Joanne Delaney (ACTG) and Robert Tucker (HVTN). Also, the Multi-Regional Clinical Trials Center of Brigham and Women’s Hospital and Harvard University is a research and policy center where multidisciplinary teams collaborate to identify challenges and deliver ethical, actionable, and practical solutions for the global clinical trial enterprise, with a focus on emerging economies.

Center for Virology and Vaccine Research’s mission is to move one step closer to the development of a cure or preventive approach for certain infectious diseases, such as Human Immunodeficiency Virus (HIV), Zika Virus and COVID-19. Their goal is to inspire and incorporate volunteers from every race, ethnicity, and gender background to join them in this mission. Together, they can move forward with these exciting developments!

Learn how you can participate in their clinical studies and join the volunteer registry here.

ClinicalTrials.gov is a online database of clinical research studies and information about their results. The purpose of ClinicalTrials.gov is to provide information about clinical research studies to the public, researchers, and health care professionals. Access the feed below or click here.

Clinical Trials.gov (new and existing studies added or modified in the last 14 days) See below – live RSS FEED

• Comparative Effectiveness of Individual Versus Group-Level Interventions to Reduce Human Immunodeficiency Virus (HIV)/ Sexually Transmitted Infections (STI) Incidence
• Estradiol Therapy In Transgender Women to Research Interactions With HIV Therapy
• Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN 102)
• Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living With HIV-1 on Suppressive Antiretroviral Therapy

Search a registry of federally and privately supported clinical trials conducted in the United States and around the world.

The Fenway Institute (TFI) is always looking for community members who want to make a difference in LGBTQI+ health and wellness by participating in research. A list of studies that are currently recruiting new participants is available here.

If you are interested in learning more, or want to find out if you may be eligible to participate, please fill out this form or contact The Fenway Institute directly at 617.927.6450.

If you have any questions about privacy protection or your rights as a research participant, you may contact The Manager of Research Integrity and Compliance at 617-927-6031. The Manger of Research Integrity and Compliance can put you in touch with the Fenway Health Institutional Review Board.

The studies at MGH are conducted by the AIDS Clinical Trials Group (ACTG). If you are interested in participating in a study, call ACTG at (617) 726-3819 to speak with a study nurse. Always talk with your primary care provider about any study you are interested in to make sure it is right for you.

The Infectious Diseases Clinical Research Unit (ID CRU) within the Division of Infectious Diseases at Massachusetts General Hospital supports investigators in the coordination and conduct of clinical trials within scientifically relevant areas of infectious diseases and provides training to infectious diseases fellows and faculty in clinical trials methodology, implementation, analysis, and interpretation. To access the ongoing clinical trials under this branch see here.

To access the NIH Clinical Studies database click here.

The Ragon Institute of Mass General, MIT, and Harvard brings together scientists and engineers from diverse fields to better understand the immune system and support human health.

The Clinical Platform at Ragon recruits subjects into their specimen collection studies and first-in-human trials. Specimens include blood, leukapheresis, mucosal swabs, sputum and saliva samples, urine, stool and microbiome collections, as well as several tissue biopsy types. These samples provide Ragon investigators with valuable information on how the body responds to HIV and other infectious diseases. You can meet the team here and contact Drs. Douglas S. Kwon and Daniel Worrall.

Rally is an online platform that supports collaboration between the public and the research community. Visit the Rally with Mass General Brigham website to find clinical research studies that meet your interests.

You can save a search or sign up for weekly e-mails to receive the latest information about studies looking for volunteers. To access all HIV clinical trials see here.